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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CALU
All Species:
29.39
Human Site:
Y218
Identified Species:
64.67
UniProt:
O43852
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43852
NP_001124146.1
315
37107
Y218
E
E
Y
I
G
D
M
Y
S
H
D
G
N
T
D
Chimpanzee
Pan troglodytes
XP_522670
331
38672
F233
D
E
Y
I
A
D
M
F
S
H
E
E
N
G
P
Rhesus Macaque
Macaca mulatta
XP_001091280
319
37387
Y222
E
E
Y
I
G
D
M
Y
S
H
D
G
N
T
D
Dog
Lupus familis
XP_849335
315
37059
Y218
E
E
Y
I
G
D
M
Y
S
H
D
G
N
A
D
Cat
Felis silvestris
Mouse
Mus musculus
O35887
315
37045
Y218
E
E
Y
I
G
D
M
Y
S
H
D
G
N
A
D
Rat
Rattus norvegicus
O35783
315
36978
Y218
E
E
Y
I
G
D
M
Y
S
H
D
G
N
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509670
315
37119
Y218
E
E
Y
I
G
D
M
Y
S
H
D
G
N
A
D
Chicken
Gallus gallus
Q5ZKE5
356
41889
E261
S
L
P
V
G
T
V
E
N
Q
Q
A
Q
D
I
Frog
Xenopus laevis
Q6IP82
315
37037
Y218
E
E
Y
I
G
D
M
Y
N
H
D
G
D
A
N
Zebra Danio
Brachydanio rerio
Q7SXV9
315
37316
Y218
N
E
Y
I
G
D
M
Y
S
Q
N
G
D
S
S
Tiger Blowfish
Takifugu rubipres
O93434
322
38188
F224
D
E
Y
I
A
D
M
F
A
H
E
D
R
G
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.7
98.7
99.3
N.A.
98
88.5
N.A.
96.1
28
80.9
76.8
59.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
75.2
98.7
99.6
N.A.
99
94.5
N.A.
98.7
51.4
90.1
87.9
77.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
100
93.3
N.A.
93.3
93.3
N.A.
93.3
6.6
73.3
60
40
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
100
93.3
N.A.
93.3
93.3
N.A.
93.3
26.6
93.3
80
66.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
19
0
0
0
10
0
0
10
0
46
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
0
0
0
91
0
0
0
0
64
10
19
10
55
% D
% Glu:
64
91
0
0
0
0
0
10
0
0
19
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
82
0
0
0
0
0
0
73
0
19
0
% G
% His:
0
0
0
0
0
0
0
0
0
82
0
0
0
0
0
% H
% Ile:
0
0
0
91
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
91
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
19
0
10
0
64
0
10
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
19
% P
% Gln:
0
0
0
0
0
0
0
0
0
19
10
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
73
0
0
0
0
10
10
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
19
0
% T
% Val:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
91
0
0
0
0
73
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _